Genestra – Pantothenic Acid

Vitamin B₅ for the maintenance of good health
• Helps to maintain the body’s ability to metabolize nutrients
• Helps in tissue formation
• Provides 500 mg of pantothenic acid per daily dose

Pantothenic acid is primarily present in the liver, kidneys and heart.¹ It is essential for the formation of coenzyme-A (CoA) and acyl-carrier protein (ACP), two compounds that donate acyl groups.¹ As acyl group metabolism is required for the production of the neurotransmitter acetylcholine, the central nervous system also needs a steady level of the vitamin.¹ CoA is a cofactor for approximately four percent of the enzymes in humans, and its acetyl-CoA form is especially important for several metabolic reactions.¹ It is required for incorporating fatty acids into membrane phospholipids and triglycerides, and is used to generate energy in the Krebs cycle.¹ Both acetyl-CoA and ACP also help mediate fatty acid synthesis.¹ Recent research indicates that pantothenic acid helps maintain the natural barrier of the skin by promoting the growth of skin cells via keratinocyte growth factor production.²

References
1. Combs, GF. (2012). In The Vitamins (4th ed., pp. 339-348). Elsevier.
2. Kobayashi, D, Kusama, M, Onda, M, Nakahata, N. J Pharmacol Sci. 2011; 115:  230 – 234.