Genestra – Digest Gluten Chewable

Great-tasting formula that may help support gluten digestion^

• Features Tolerase^® G Prolyl Endopeptidase, which has been clinically demonstrated to help break down residual gluten in meals
• Ideal for gluten-sensitive individuals concerned about hidden gluten in food
• Supports healthy digestive function
• Delicious natural cherry-berry flavoured chewable tablet format

Digest Gluten Chewable was specifically formulated for gluten-sensitive individuals who are trying to follow a gluten-free or gluten-reduced diet. Gluten is abundant in the Western diet in grains and processed foods, and can be present in non-food items such as medication, toothpaste, mouthwash and lipstick.^1,2 As individuals have less control over their food when travelling, during social visits or at restaurants, it may be difficult to intentionally limit gluten intake.³ Furthermore, contamination of gluten-free foods may occur during processing, packaging or storage, and through sharing utensils or appliances.³ Digest Gluten Chewable features Tolerase^® G, a prolyl endopeptidase that has been clinically shown to help break down gluten peptides in the stomach.^4,5 In one study, Tolerase^® G degraded nearly all of the gluten present in the stomach of participants within one hour of administering a liquid low- or high-calorie, gluten-containing meal.⁴ Additionally, this enzyme significantly degraded gluten in the stomach and duodenum of participants after consumption of gluten-containing porridge.⁵ Preclinical research has found that Tolerase^® G is active at the low-pH range of the stomach, resistant to pepsin degradation and able to degrade the immunogenic peptides of gluten, further supporting its use as an effective enzyme.⁶ Each delicious chewable tablet can be easily incorporated into the diet to help in the digestion of gluten-containing foods.^4,5

^This product is not intended to replace a gluten-free diet, or to treat or prevent celiac disease.

REFERENCES
1. Biesiekierski, JR. J Gastroenterol Hepatol. 2017; 32 (Suppl. 1): 78–81.
2. See, J, Murray, JA. Nutr Clin Pract. 2006; 21(1): 1-15.
3. Samasca, G, Lerner, A, Girbovan, A, Sur, G, Lupan, I, et al. Eur J Clin Invest. 2017; 47(5):394-397.
4. Salden, BN, Monserrat, V, Troost, FJ, Bruins, MJ, Edens, L, et al. Aliment Pharmacol Ther. 2015; 42(3): 273-85.
5. König, J, Holster, S, Bruins, MJ, Brummer, RJ. Sci Rep. 2017; 7: 13100.
6. Stepniak, D, Spaenij-Dekking, L, Mitea, C, Moester, M, de Ru, A, et al. Am J Physiol Gastrointest Liver Physiol. 2006; 291(4): G621-9.

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