Genestra – Active Multi Vite

Contains physiologically active forms of riboflavin, vitamin B₆, folate and vitamin B₁₂¹
• Helps in the development and maintenance of bones, cartilage, teeth and gums
• Helps to maintain proper muscle function, immune function and healthy skin
• Provides antioxidant for the maintenance of good health
• Includes 1000 IU of vitamin D and 27.5 mg of magnesium per daily dose

Active Multi Vite is a vegetarian-friendly formula providing a combination of vitamins and minerals that help support bone and muscle health. It is estimated that nearly one third of Canadians have low vitamin D levels.2 Vitamin D promotes the activity of bone cells for proper bone remodeling, and helps absorb and use calcium and phosphorus for normal bone mineralization.² Research demonstrates that 600 IU of vitamin D daily helps maximize bone health in adults.^3,4 Among adults over 70 years of age, 800 IU daily helps maximize bone health and may help decrease the risk of hip or non-vertebral fractures by nearly 25%.^4,5 Beta carotene is source of vitamin A that further contributes to the development and maintenance of bones and teeth. Approximately half of magnesium is located in bones, where it stimulates bone forming osteoblast activity.⁶ Magnesium is also essential for promoting muscle function as it competes with calcium for binding sites on proteins that regulate muscle contractions.⁶ During rest, magnesium is bound to these sites; however, during periods of low magnesium, calcium binds the proteins, which may result in hypercontractibility and muscle cramps.⁶ As nearly 80-90% of magnesium is lost after food processing, its supplementation helps to maintain good health.⁶

References
1. Combs, GF. (2012). The Vitamins (4th ed.). USA: Elsevier.
2. Statistics Canada. 2013. Retrieved from: < http://www.statcan.gc.ca/pub/82-624-x/2013001/article/11727-eng.htm>.
3. Wranicz, J, Szostak-Wegierek, D. Characteristics and Classic Role. Rocz Panstw Zakl Hig. 2014; 65(3): 179-184.
4. Holick, MF, Binkley, NC, Bischoff-Ferrari, HA, Gordon, CM, Hanley, DA, Heaney, RP, Murad, MH, Weaver, CM. J Clin Endocrinol Metab. 2011; 96(7):1911-1930.
5. Bischoff-Ferrari, HA, Willett, WC, Wong, JB, Giovannucci, E, Dietrich, T, Dawson-Hughes, B. JAMA. 2005; 293(18): 2257-2264.
6. de Baaij, JHF, Hoenderop, JGJ, Bindels, RJM. Physiol Rev. 2015; 95: 1-46.

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