Genestra – Active B6 Pyridoxal

Vitamin B₆ in its most active form
• Helps in tissue formation
• Supports and maintains good health
• Helps the body to metabolize carbohydrates fats, and proteins
• Helps to prevent vitamin B₆ deficiency
• Provides 50 mg of vitamin B₆ per capsule

Active B₆ Pyridoxal is a source of vitamin B₆ in the form of pyridoxal-5-phosphate (PLP). As the most biologically active form of the vitamin, PLP helps to catalyze over
140 reactions.¹ PLP is an important cofactor in: 1) fatty acid metabolism, including the production of important omega-6 polyunsaturated fatty acids; 2) carbohydrate metabolism, including the breakdown of glycogen into glucose; 3) amino acid metabolism, including neurotransmitter synthesis and the conversion of tryptophan into niacin.¹ Vitamin B₆ deficiency decreases niacin production and increases formation of the metabolite xanthurenic acid, which lowers insulin activity.² Low levels of vitamin B₆ also lead to increased synovial fluid between joints, which results in nerve compression.³

References
1. Mooney, S, Leuendorf, JE, Hendrickson, C, Hellmann, H. Molecules. 2009; 14: 329-351.
2. Oxenkrug, G. Mol Neurobiol. 2013; 48(2): 294-301.
3. Combs, GF. (2012). In The Vitamins (4th ed., pp. 309-323). Elsevier.

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