Genestra – Biotone EFA

Combination of free plant sterols from Glycine max bean
• Helps lower blood total and LDL cholesterol
• Provides 896 mg of free plant sterols per daily dose
• Source of antioxidants and essential fatty acids for the maintenance of good health
• Includes 10 IU of mixed tocopherol antioxidants per daily dose
• Provides 1392 mg of linoleic acid and 144 mg of ALA per daily dose

Biotone EFA is an effective blend of lecithin-derived free plant sterols, essential fatty acids, and antioxidants that helps to maintain optimal health. Once in the free form, plant sterols affect cholesterol absorption in the intestine.¹ Plant sterols displace dietary cholesterol in micelles, resulting in increased cholesterol excreted in the feces and decreased serum cholesterol levels.^2,3 In a randomized, placebo-controlled trial involving 66 hypercholesterolemic adults, daily supplementation with 0.3-0.5 g of plant sterol esters significantly decreased LDL cholesterol levels in a dose-dependent manner within four weeks.⁴ Antioxidants further maintain good health by scavenging free radicals to prevent oxidative damage.⁵

REFERENCES
1. De Smet, E, Mensink, RP, Plat, J. Mol. Nutr. Food Res. 2012; 56: 1058–1072.
2. Gylling, H, Plat, J, Turley, S, Ginsberg, HN, Ellegård, L, Jessup, W, Jones, PJ, Lütjohann, D, Maerz, W, Masana, L, Silbernagel, G, Staels, B, Borén, J, Catapano, AL, De Backer, G, Deanfield, J, Descamps, OS, Kovanen, PT, Riccardi, G, Tokgözoglu, L, Chapman, MJ. Atherosclerosis. 2014; 232: 346-360.
3. Cusack, LK, Fernandez, ML, Volek, JS. Adv Nutr. 2013; 4(6): 633-43.
4. Saito, S, Takeshita, M, Tomonobu, K, Kudo, N, Shiiba, D, Hase, T, Tokimitsu, I, Yasukawa, T. Nutrition. 2006; 22: 174–178.
5. Walczak–Jedrzejowska, R, Wolski, JK, Slowikowska–Hilczer, J. Central European Journal of Urology. 2013; 66(1): 60-67.

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