Genestra – TPIN (pineal )

Vitamin B₆ in its active form
? Helps in tissue formation
? Helps the body metabolize carbohydrates, fats and proteins
? Helps to prevent vitamin B₆ deficiency
? Provides 20 mg of vitamin B₆ per daily dose

TPIN is a source of vitamin B₆ in the form of pyridoxal-5-phosphate (PLP). As the most biologically active form of the vitamin, PLP helps to catalyze over 140 reactions.¹ Vitamin B₆ participates in nearly all metabolic reactions involving amino acids, including their synthesis and breakdown.¹ Approximately 70-80% of vitamin B₆ is present in muscle, where it acts as a coenzyme for glycogen phosphorylase.¹ This enzyme is necessary for glycogenolysis, which breaks down glycogen into glucose and provides fuel to muscle during exercise.¹ Low levels of vitamin B₆ also lead to increased synovial fluid between joints, which results in nerve compression.² Eleuthero root is a thorny shrub native to Siberia and northern parts of China, and its beneficial health effects arise from the high levels of lignans in its roots.³ TPIN also contains an extract from Ginkgo biloba, an ancient plant traditionally used in Chinese medicine.⁴ Ginkgo contains flavonoids, terpenoids and proanthocyanidins, which are responsible for its positive health effects.⁴

References
1. Mooney, S, Leuendorf, JE, Hendrickson, C, Hellmann, H. Molecules. 2009; 14: 329-351.
2. Combs, GF. (2012). In The Vitamins (4th ed., pp. 309-323). Elsevier.
3. Murthy, HN, Kim, YS, Georgiev, MI, Paek, KY. Appl Microbiol Biotechnol. 2014; 98: 7319-7329.
4. Brondino, N, De Silvestri, A, Re, S, Lanati, N, Thiemann, P, Verna, A, Emanuele, E, Politi, P.  Evidence-Based Complementary and Alternative Medicine. 2013; 2013: 915691.

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