Genestra – TBMP (Medulla Complex)

Thiamine and choline for optimal health
? Helps the body to metabolize carbohydrates, fats and proteins
? Helps in normal growth
? Helps to prevent thiamine deficiency
? Provides 24 mg of thiamine per daily dose
? Includes 100 mg of choline per daily dose

TBMP is a combination of thiamine and choline, two factors in the maintenance of good health. Thiamine is an essential cofactor in carbohydrate, fat and protein metabolism.¹ It is necessary for the normal activity of four enzymes involved in: 1) conversion of pyruvate into acetyl-CoA for energy production in the Krebs cycle; 2) conversion of ?-ketoglutarate into succinyl CoA in the Krebs cycle; 3) synthesis of nucleic acids and lipids; 4) breakdown of branched-chain amino acids.¹ As thiamine is involved in the synthesis of glucose in the Krebs cycle, decreased levels of the vitamin are associated with reduced synthesis of ATP for energy production.¹ Deficiencies in thiamine may also lead to decreases in complexin I and II, proteins that regulate the release of neurotransmitters.² Choline is an essential nutrient that can be converted into phosphatidylcholine, an important component of lipid membranes, or acetylcholine, a key neurotransmitter involved in learning and sleep.^1,3

References
1. Combs, GF. (2012). The Vitamins (4th ed.). USA: Elsevier.
2. Abdou, E, Hazell, AS. Neurochem Res. 2015; 40: 353-361.
3. Li, Z, Vance, DE. J. Lipid Res. 2008; 49: 1187-1194.

Download Product Information

• Supplement Facts